The KIDDRC proposes to operate four Cores in support of its projects:
Administrative and Communications Core. The Administrative and Communications Core will coordinate and integrate services and functions across the three physical locations of the KIDDRC (KU-L, KUMC, and JGCP). The AC provides scientific leadership and governance mechanisms to ensure that scientific cores are responsive to changing needs and new scientific directions.
Clinical Translational Core. The Clinical Translational Core will provide KIDDRC investigators with tools for enhancing translational research. The CTC facilitates contact with individuals with IDD for research by providing access to an integrated repository and other regional databases, by maintaining and expanding registries for access to populations of children with well-characterized IDD and typically-developing (TD) children, and by facilitating contact with community organizations and facilities that serve populations of interest to projects in the KIDDRC portfolio.
Preclinical Models Core. The Preclinical Models Core will facilitate translational applications by assisting in the development of cellular and organismal models of IDD. This is done by providing infrastructure and resources needed to create and characterize laboratory models of IDD, and by extending KIDDRC’s prior capabilities for analyzing behavior, anatomy, physiology and gene expression.
Research Design and Analysis Core. The Research Design and Analysis Core will support analysis of data from both preclinical and clinical research through state-of-the-art statistical and bioinformatics methods. Appropriate scientific design and analysis is critical to the validity and impact of all research conducted within the themes of the KIDDRC.